USB ports shut off when Rockband VR starts

I'm trying to get Rock Band VR to work for the first time. I'm having a problem now that when the game is getting ready to start all of a sudden my USB ports on my computer shut down. It seems to be all the ports except the ones Oculus is using. I haven't had this problem playing other games. The ports will not come back on and since it includes my mouse and keyboard I can't do anything except hard reset the computer. Any advice for what's going on, how to fix it? Thanks